Vol. 1 nº 3 - Jul/Aug/Set de 2007
Original Article Páginas: 230 a 240

Systematic review of dementia prevalence - 1994 to 2000

Authors Marcos Antonio Lopes1,2, Sérgio Ricardo Hototian2, Geraldo C. Reis1, Hélio Elkis3, Cassio Machado de Campos Bottino2


keywords: epidemiology, prevalence, dementia, Alzheimer disease, review.

Ageing has occurred in all regions of the world, with impact on neuropsychiatric disorders, particularly dementia. However, previous meta-analysis and reviews have shown high variability in world dementia prevalence rates. Objective: The aim of this study was to perform a wide-ranging review of the dementia prevalence studies published in recent years. Methods: The search was made on Medline, Lilacs and Embase databases for research conducted between 1994 and 2000. The main inclusion criteria were: use of standard diagnostic criteria and investigation of community samples. Results: The fi nal selection included 42 papers, from all continents. The mean prevalence rate of dementia in subjects aged 65 years and older, for continents, ranged from 2.2% in Africa to 8.9% in Europe, and among countries, from 1.3% in India to 14.9% in Spain. However, there was a trend of clustering of the world prevalence rates with the majority of studies reporting rates between 4.2% and 7.2% (.65 years). Age directly infl uenced the rates, with a mean prevalence rate of 1.2% (95% CI: for the 65-69 years group and 39.9% (95% CI: for the 90-94 year group, but showing less pronounced infl uence in the very elderly age group. The urban samples had higher rates, where no signifi cant gender difference was evidenced. Conclusion: The age infl uence over dementia rates apparently leveled off in the very elderly group while a trend toward similar dementia prevalence rates around the world was probably infl uenced by greater homogeneity in diagnostic criteria.


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