Vol. 13 nº 4 - Oct/Nov/Dec de 2019
Original Article Páginas: 469 a 474

Sundown syndrome in patients with Alzheimer's disease dementia

Authors Cristiani Sartorio Menegardo1; Fernanda Alencar Friggi1; Julia Baldon Scardini2; Tais Souza Rossi2; Thais dos Santos Vieira2; Alessandra Tieppo3; Renato Lirio Morelato4


keywords: Alzheimer's disease; elderly; neuropsychiatric symptom; sundown syndrome.

OBJECTIVE: To analyze the main neuropsychiatric symptoms, their correlation with one another, with comorbidities, and with time of day of greatest symptom intensity in patients with Alzheimer's disease dementia.
METHODS: This is a cross-sectional, observational and explanatory study in which caregivers/relatives of elderly patients with dementia were interviewed using a structured tool called the Neuropsychiatric Inventory (NPI).
RESULTS: The sample studied was composed of 38 patients, 60.5% female and 39.5% male, with mean age of 81±6 (67-94) years. A high frequency of neuropsychiatric symptoms in the evening period was observed, predominantly irritability (55.3%), nocturnal behavior (47.4%), and aggressiveness (42.1%). Only 36.8% of the family caregivers used non-pharmacological strategies.
CONCLUSION: The frequency of neuropsychiatric symptoms was exacerbated in the evening among patients with Alzheimer's disease, especially for those behavioral symptoms that had a positive correlation with one another.


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