Vol. 12 nº 1 - Jan/Feb/Mar de 2018
Original Article Páginas: 19 a 27

Cognitive deficits in older adults with mild cognitive impairment in a two-year follow-up study

Authors Camila de Assis Faria1; Heloisa Veiga Dias Alves1; Eduarda Naidel Barboza e Barbosa1; Helenice Charchat-Fichman2

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keywords: mild cognitive impairment, dementia, cognitive decline, conversion, cognitive trajectory.

ABSTRACT:
Characterizing cognitive decline in older adults with MCI over time is important to identify the cognitive profile of those who convert to dementia.
OBJECTIVE: This study examined the two-year cognitive trajectory of elderly adults diagnosed with MCI, from geriatrics and neurology outpatient clinics of a public hospital in Rio de Janeiro.
METHODS: 62 older adults with MCI were submitted to a neuropsychological battery and re-evaluated after two years. The Mann-Whitney U test was employed to assess differences between groups with respect to education, functioning, the Geriatric Depression Scale and diagnosis.
RESULTS: 24.2% converted to dementia after two years. The group with declines in two or more cognitive functions had a higher conversion rate to dementia than the group with decline in executive functions (EF) only (Z = -2.11, p = .04). The EF decline group had higher scores on the depression scale than both the memory decline group (Z = -1.99, p = .05) and multiple decline group (Z = -2.23, p = .03).
CONCLUSION: The present study found different cognitive decline profiles in elderly adults with MCI and differences between them regarding depressive symptoms and rate of conversion to dementia.

 

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