Vol. 11 nº 3 - Jul/Aug/Set de 2017
Short Communication Páginas: 297 a 300

High education accelerates cognitive decline in dementia: A brief report from the population-based NEDICES cohort

Authors Israel Contador1; Félix Bermejo-Pareja2,3,4; D. Lora Pablos5; Alberto Villarejo6; Julián Benito-León3,4,6


keywords: dementia, education, cognitive decline, population-based.

High education has been associated with faster cognitive decline after diagnosis of Alzheimer's disease (AD), but it is unclear whether these findings extend to other dementia subtypes.
OBJECTIVE: We investigated whether educational attainment influences the cognitive trajectories of older adults with different dementia subtypes.
METHODS: All participants were selected from NEDICES, a prospective population-based cohort study of Spanish older adults. A total sample of 53 individuals with dementia completed the MMSE-37 at Times 1 and 2 (mean follow-up=2.8±0.5 years) to assess cognitive decline.
RESULTS: At follow-up, MMSE-37 scores had decreased by 3.34±4.98 points in low-educated individuals with dementia versus 7.90±4.88 points in high-educated subjects (effect size (r)=0.32, p=0.02).
CONCLUSION: Educational level influenced the cognitive trajectories of patients with dementia assessed by the MMSE-37.


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