Vol. 2 nº 2 - Apr/May/Jun de 2008
Original Article Páginas: 91 a 95

Neuropsychological alterations in mercury intoxication persist several years after exposure

Authors Elaine Cristina Zachi1, Anita Taub2, Marcília de Araújo Medrado Faria3, Dora Fix Ventura4

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keywords: mercury, occupational exposure, cognition disorders, neuropsychological tests, mood.

ABSTRACT:
Elemental mercury is a liquid toxic metal widely used in industry. Occupational exposure occurs mainly via inhalation. Previously, neuropsychological assessment detected deficits in former workers of a fluorescent lamp plant who had been exposed to elemental mercury vapor and were away from exposure for several years at the time of examination. Objectives: The purpose of this work was to reexamine these functions after 18 months in order to evaluate their progression. Methods: Thirteen participants completed tests of attention, inhibitory control, verbal/visual memory, psychomotor speed, verbal fluency, visuomotor ability, executive function, semantic knowledge, and depression and anxiety inventories on 2 separate occasions. Results: At baseline, the former workers indicated slower psychomotor and information processing speed, verbal spontaneous recall memory impairment, and increased depression and anxiety symptoms compared to controls (P<0.05). Paired comparisons of neuropsychological functioning within the exposed group at baseline and 1.5 years later showed poorer immediate memory performance (P<0.05). There were no differences on other measures. Conclusions: Although the literature show signs of recovery of functions, the neuropsychological effects related to mercury exposure are found to persist for many years.

 

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