Vol. 6 nº 3 - Jul/Aug/Set de 2012
Case Report Páginas: 192 a 195

Vascular cognitive impairment in Pemphigus vulgaris: a case report

Authors José Ibiapina Siqueira-Neto1; Paulo Marcelo Gondim Sales2; Emmanuelle Silva Tavares Sobreira3; Aline Miranda Limeira4; Heline Bessa Araujo5; Júnia Vieira dos Santos6; José Daniel Vieira de Castro7


keywords: Pemphigus vulgaris, cognitive vascular impairment, neuropsychological testing, auto-immune diseases, dementia.

Pemphigus vulgaris is a systemic auto-immune medical condition that mainly manifests with changes in skin and vasculopathy. This is a case report of a 69-year-old male with confirmed histopathologic diagnosis of Pemphigus vulgaris presenting ulterior Cognitive Impairment, mostly in executive function. The patient was treated using steroids, immunomodulatory therapy, fluoxetine and galantamine. Neuropsychological testing and magnetic resonance (MRI) were performed. This is the first report of correlational cognitive impairment with Pemphigus vulgaris in the literature. Physicians should be aware of vascular causes for cognitive impairment in patients presenting auto-immune conditions.


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