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Figure 1
Description: Figure 1. Neuropathological features of argyrophilic grain disease. All the histological slides are immunostained with PHF-1 antibody against phospho-tau. (A) Argyrophilic grains spread in the neuropil of region CA1 of the hippocampus. 400×. (B) The same as in A. Note a pre-tangle in the picture. 400×. (C) Coiled body (arrow) in an oligodendrocyte in the white matter adjoining the entorhinal cortex. 400×. (D) Pre-tangles in the dentate gyrus (arrows). 400×. (E) Pre-tangles in the CA1 region of the hippocampus. Note the difference of the phospho-tau aspect between pre-tangles (diffuse) and the tangles (neurofibrillary) to the bottom right.
Article Details
Vol. 3 nº 1 - Jan/Feb/Mar - 2009
Argyrophilic grain disease: an update about a frequent cause of dementia
Authors: Lea T. Grinberg1,2, Helmut Heinsen2

 

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